Knowledge of species-specific behavior helps vets handle animals safely and with less stress.
| Drug Class | Example | Indications | Canine Dose Note | Feline Toxicity Warning | | :--- | :--- | :--- | :--- | :--- | | | Fluoxetine | Separation anxiety, CCD, generalized anxiety | 1–2 mg/kg/day | Avoid liquid suspension with xylitol | | TCA | Clomipramine | Separation anxiety, obsessive licking | 1–3 mg/kg q12h | Do not use with MAOIs | | SARI | Trazodone | Situational anxiety (vet visits, fireworks) | 3–10 mg/kg | Paradoxical excitement possible | | Alpha-2 agonist | Dexmedetomidine (oromucosal gel) | Noise aversion, acute stress | 125–375 mcg/m² | Bradycardia risk | zooskool animal sex new