If you want a simple 50-mod load order, yes. Use the latest USSEP on 1.6.x.
– Indispensable for bug fixing, but version 1.5.97 is now legacy. skyrim ussep 1.5.97
is a mandatory requirement for almost all other mods. However, the lead developer, Arthmoor, famously only supports the latest version of the game. This means if you go to Nexus Mods today, you will primarily find the version for 1.6.1170+. If you want a simple 50-mod load order, yes
The intersection of and the Unofficial Skyrim Special Edition Patch (USSEP) is a cornerstone of the "legacy" modding community. While the game has since moved to version 1.6+ (Anniversary Edition), many players deliberately maintain 1.5.97 for its superior stability and compatibility with specific SKSE plugins . The Core Version: USSEP 4.2.5b is a mandatory requirement for almost all other mods
require game files from version 1.6+, making them incompatible with the popular 1.5.97 modding base without specific workarounds. The Compatibility Conflict Version Mismatch